When it comes to messy humiliations, I find really important that the humiliated person states something after the mess (or someone does). Something funny or humiliating, of course. Some examples:

The great race:
Mr. Lemmon after being hit with a pie: "Rhum? I never mix my pies"
Me. Lemmon after falling in a pigsty: "I wonder if Leslie could beat this!!"

Singin' in tha rain: after being pied: "you never look sweeter".

Genevieve after spitting out eggnog: "What? pies weren't enough? Yeah... sure... my dress is ruined... ok... whatever... thanks..."

Well, anyone could add some more!?!?

What do you think about it?

"I can't believe you just did that!"

"I am so messy!"

"Oohh, it's in my hair!!"

"My outfit is ruined!"

"I was supposed to go out tonight!"

---This is an expensive designer suit! You ruined it!

---I was looking so elegant and now look what you did to me!

---I needed an hour to do my hair, it's messed up now!

---Do you know how expensive this necktie was?

--Oh Noooooo, please stop it!

---Not my hair please!!!

I think it helps make the scene but there aren't a lot of producers that get that.

"I didn't see that coming..."

"I haaaate pies!!"

"I think I need some make up..."

"It could be worse... It could be a pie.." SPLAT!!

"Why's it still dripping on me?" is a favourite of mine.

(nods) "Perfect."

"Check, please!"

"Mmm, COCONUT!"

"You wouldn't!"

"I would."

"You couldn't!"

"I could."

"You shouldn't!"

"I should!"

[Model is pied]

"Yeah...you did."

I constantly have my Divas "taunt" one another with verbal quips.

(after hitting your friend with a blue pie)
"Oh, sweetheart, why so blue???"
"Hey, look, It's Smurfette."
"Trying out for the new Avatar movie, are we??"

(after hitting your friend with a red pie)
"Boy, is your face red."
"The devil made me do it."
"Toe-may-toe, Toe-mah-toe, let's call the whole thing off."

(after hitting your friend with a green pie)
"I can see you are just green with envy how much more beautiful I am."
"They already cast the She-Hulk, girlfriend."

You can see several of these quips
(and much more) on my "Albums" page
and my three Tournament threads from March.

The line, the delivery and the timing all matter to create the comedy. I've seen a few flubs that have ruined it before. I wish more directors would take the time to rehearse the scenes with their actresses, so they could refine that timing and delivery, and help those reactions come naturally.
Seeing the actress state a line too soon, wait for the mess to stop coming, and then repeat the line just gives away how scripted yet poorly rehearsed the scene was.

Conversely, when a scene is set well for timing, we get to see some great facial reactions when the mess comes, feel the build as it finishes, and then we're all ready to hear the line delivered at the end, putting a button on the gag and elevating it into slapstick art.

I love it when people announce how they're feeling after being gunged..

"Eww it smells"

"I'd only just washed my hair"

"Oh it feels amazing"

"It's still dripping on me"

After receiving a pie in the face :
-Mmm it tastes good, it's very sweet
-Mmm yummy!

I like it when the gunging is enjoyed.

When Lee Ryan was snotted on TV, he said, "I quite enjoyed it."

When Ben Adams was gunged on TV, he said, "It was quite turning on in a way."

Definitely great to hear these responses and when the gunge is embraced.